As far as I know, Reason doesn't support a global pedal-off mechanism. I hope someone will chime in on this issue and recommend a workaround.
It seems one way this could work if pressing the "next/prev patch" button first fired a "pedal off" message. Since Reason doesn't support that kind of programming, I'm wondering if it can be done *before* the MIDI signal reaches Reason. I know there's MIDI hardware and software that lets you intercept and modify MIDI messages on the fly. We'd have to intercept the "next patch" message and prepend it with a "pedal off" message. I'll look into it.
By the way, what kind of MIDI controller are you using? And how many patches do you use in your live setup?