This DIY point of view has an elitist/macho ring to it. Personally I'm not interested in endless tinkering. Im not a hardcore screwdriver man, I want to spend my time making music.
I use Podfarm Platinum in Reason, which provides easy access to a lot of tones to get there quickly. But an Amplitude RE or Guitar Rig etc would be welcome yet....
All the main DAWS have their own amp emulation as well as the ability to plug in external ones. To pretend Reason does not need this is sheer fanboy denialism.